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Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
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Development and Assessment of Intracellular Infection Models for Staphylococcus aureus

Published on: January 17, 2025

Treatment of Staphylococcus aureus infections: new issues, emerging therapies and future directions

Emma J Bishop1, Benjamin P Howden

  • 1Austin Health, Infectious Diseases Department, Studley Road, Heidelberg, 3084, Victoria, Australia.

Expert Opinion on Emerging Drugs
|March 16, 2007
PubMed

Insights

Staphylococcus aureus infections pose a global health threat due to rising antimicrobial resistance. This review covers current and novel therapies, including immune-based strategies, for treating S. aureus infections and combating resistance.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Pharmacology

Background:

  • Staphylococcus aureus infections are a significant global cause of illness and death.
  • Antimicrobial resistance in S. aureus, including methicillin and glycopeptide resistance, is a growing challenge.
  • Emerging resistance necessitates the development of new treatment strategies.

Purpose of the Study:

  • To review established and emerging therapies for Staphylococcus aureus infections.
  • To evaluate the safety and potential impact of novel antimicrobial agents.
  • To explore immune-based strategies for S. aureus infection prevention and treatment.

Main Methods:

  • Literature review of established and emerging S. aureus therapies.
  • Analysis of clinical development stages for novel agents.
  • Assessment of safety profiles and potential clinical impact.

Main Results:

  • New antimicrobials for S. aureus are entering the market or in late-stage development.
  • Significant research interest exists in novel and immune-based treatment strategies.
  • Established therapies are being augmented by emerging options.

Conclusions:

  • A range of new therapies are becoming available to combat S. aureus infections.
  • Novel agents and immune-based strategies offer promise in addressing antimicrobial resistance.
  • Understanding safety profiles and clinical impact is crucial for evolving treatment standards.

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