Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Borderline Personality Disorder01:25

Borderline Personality Disorder

Borderline Personality Disorder is a complex and multifaceted mental health condition characterized by pervasive instability in interpersonal relationships, self-image, emotions, and impulse control. This instability manifests in extreme emotional reactions, fear of abandonment, and self-destructive behaviors. The disorder significantly impacts daily functioning, often leading to distress in both personal and professional domains.
Genetic and Environmental Contributions
Borderline Personality...
Bipolar Disorder01:30

Bipolar Disorder

Bipolar disorder is a chronic mental health condition marked by significant mood fluctuations, including episodes of mania and depression. Elevated energy levels, heightened mood or irritability, impulsive behavior, reduced sleep needs, rapid speech, racing thoughts, inflated self-esteem, and distractibility characterize mania. Individuals with bipolar disorder often alternate between depressive and manic states, with periods of emotional stability lasting an average of six months to a year.
Personality Disorders: Dependent and Obsessive-Compulsive01:24

Personality Disorders: Dependent and Obsessive-Compulsive

Dependent personality disorder and obsessive-compulsive personality disorder are two separate psychological conditions that influence behavior, relationships, and overall life functioning. Though both involve maladaptive behaviors, their core characteristics and motivations differ significantly.
 Dependent Personality Disorder
Dependent personality disorder is characterized by an excessive reliance on others to manage various aspects of life. Individuals with this disorder often struggle with...
Personality Disorders: Schizotypal and Histrionic01:20

Personality Disorders: Schizotypal and Histrionic

Schizotypal personality disorder and histrionic personality disorder are two distinct psychological conditions classified under personality disorders, each characterized by unique behavioral patterns and social difficulties. Both disorders significantly affect interpersonal relationships and emotional well-being, leading to social isolation and frustration.
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...
Personality Disorders: Narcissistic and Avoidant01:26

Personality Disorders: Narcissistic and Avoidant

Narcissistic and avoidant personality traits represent two contrasting patterns of behavior that significantly influence social interactions and self-perception. While individuals with narcissistic disorder seek admiration and validation, individuals with avoidant personality disorder withdraw due to fear of judgment.
Characteristics of Narcissistic Personality Disorder
Narcissistic individuals exhibit an inflated sense of self-importance and an excessive need for admiration. They are often...
Personality Disorders: Paranoid and Schizoid01:22

Personality Disorders: Paranoid and Schizoid

Personality disorders represent enduring cognition, affect, and behavior patterns that significantly deviate from societal norms. These maladaptive traits often lead to difficulties in various domains, including interpersonal relationships, occupational settings, and overall psychological well-being. Paranoid personality disorder and schizoid personality disorder are two distinct conditions marked by odd or eccentric behavior.
Paranoid Personality Disorder
Paranoid personality disorder is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Haploidentical Sibling Donors for Pediatric Patients: The Perfect Mismatch?

European journal of haematology·2026
Same author

Mitigating Excessive Mitochondrial Fission Through the Development of a Selective Macrocyclic Inhibitor Targeting Fis1/Mid51 Signaling.

Journal of medicinal chemistry·2026
Same author

Safety, tolerability, and efficacy of atogepant added to onabotulinumtoxinA for the preventive treatment of chronic migraine: A phase 3, multicenter, 24-week, open-label study.

Cephalalgia : an international journal of headache·2026
Same author

From tool to teammate in a randomized controlled trial of clinician-AI collaborative workflows for diagnosis.

NPJ digital medicine·2026
Same author

Artificial intelligence translation in healthcare: an urgent call for evidence-informed policy frameworks.

BMJ health & care informatics·2026
Same author

Inner Ear Histopathology of Complete Trisomy 13.

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·2026

Related Experiment Video

Updated: Jul 16, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

Borderline personality disorder and migraine.

John Rothrock1, Ivan Lopez, Richard Zweilfer

  • 1University of South Alabama Headache Center, University of South Alabama College of Medicine, Mobile, AL, USA.

Headache
|March 16, 2007
PubMed
Summary

Migraine patients with borderline personality disorder (BPD) experience more severe headaches and are less responsive to treatment. Screening tools for BPD may not be effective in headache clinics.

More Related Videos

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies
05:49

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Related Experiment Videos

Last Updated: Jul 16, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
10:39

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies
05:49

An Automated Squint Method for Time-syncing Behavior and Brain Dynamics in Mouse Pain Studies

Published on: November 1, 2024

Area of Science:

  • Neurology
  • Psychiatry
  • Clinical Research

Background:

  • Borderline personality disorder (BPD) is potentially common in migraine patients, but its specific migraine features are not well understood.
  • Understanding these features is crucial for effective patient management.

Purpose of the Study:

  • To characterize migraine patients with BPD.
  • To evaluate their response to aggressive headache management.
  • To assess the sensitivity of the McLean Screening Instrument for Borderline Personality Disorder (MSI-BPD).

Main Methods:

  • Evaluated 150 migraine patients: 50 with BPD, 50 without BPD, and 50 matched controls.
  • Assessed demographic and clinical variables.
  • Administered the MSI-BPD and a 6-month pharmacologic headache management program for two groups.

Main Results:

  • Migraine with BPD associated with female gender, pervasive headaches, disability, medication overuse headache, depression, and poor treatment response.
  • The MSI-BPD showed low sensitivity for detecting BPD.

Conclusions:

  • Migraine patients with BPD are a distinct subgroup with more severe, treatment-refractory headaches.
  • Standard BPD screening tools may be ineffective in headache clinics.