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Porous orbital implants in enucleation: a systematic review
Rajeev Chalasani1, Laura Poole-Warren, R Max Conway
1Graduate School of Biomedical Engineering, The University of NSW, Sydney, Austraia.
Survey of Ophthalmology
|March 16, 2007
Summary
Porous orbital implants offer theoretical benefits for cosmesis after enucleation, but clinical evidence is insufficient to confirm superiority over non-porous options. Future research needs long-term trials to assess complications.
Area of Science:
- Ophthalmology
- Biomaterials Science
- Surgical Innovation
Background:
- Orbital implants have been utilized for over a century to improve cosmesis after enucleation (eyeball removal).
- Recent advancements include porous biomaterials, theoretically offering reduced complications and enhanced aesthetic outcomes.
Purpose of the Study:
- To review the use of orbital implants in enucleation, focusing on porous biomaterials introduced in the last 15 years.
- To identify factors influencing the performance of porous orbital implants.
Main Methods:
- Literature review of orbital implant usage in enucleation.
- Analysis of factors affecting porous implant performance, including material, pore size, and morphology.
- Consideration of mechanical factors and future material compliance.
Main Results:
- Current clinical evidence is insufficient to establish the superiority of porous over non-porous orbital implants.
- No single porous material has demonstrated clear advantages for this application.
- Factors like material, pore size, and morphology impact porous implant performance.
Conclusions:
- Further research, particularly randomized controlled trials with long-term follow-up (over 5 years), is required to evaluate the efficacy and safety of porous orbital implants.
- Mechanical properties may be a crucial area for future development in porous orbital implant design.
