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Published on: May 31, 2016
Neuropsychologic assessment of patients with advanced Parkinson disease submitted to extradural motor cortex
Donato Munno1, Silvia Caporale, Giuseppina Zullo
1Neuroscience Department, Clinical Psychology Service, Neurosurgical Clinic, University of Turin, Turin, Italy. donato.munno@unito.it
Objective:
The aim of this study was to evaluate changes in cognitive functioning and emotive state in 3 inpatients with advanced Parkinson disease (PD) treated with extradural motor cortex stimulation (EMCS), an experimental neurosurgical procedure.
Background:
Studies on the neuropsychologic assessment of patients with PD after EMCS are in process. The procedure has been applied for some years as an experimental method for treating PD.
Method:
A battery of neuropsychologic tests and emotive assessment scales were administered to 3 inpatients with PD 2 days before the intervention and then again after 1 year to evaluate changes in cognitive functioning and emotive state.
Results:
At 1-year postintervention, cognitive functions and depressive symptoms were steady; 2 patients showed a mild improvement in quality of life.
Conclusions:
In this patient group, EMCS, an experimental neurosurgical treatment, had a positive effect on motor symptoms. Neuropsychologic assessment after a 1-year follow-up period showed that cognitive functions had not changed with respect to baseline characteristics.

