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A-5 year review of cerebral malaria in nigerian children

J B E Elusiyan1, P O Obiajunwa, I O Senbanjo

  • 1Department of Paediatrics and Child Health, Obafemi Awolowo University, Ile-Ife, Osun-State, Nigeria.

The Nigerian Postgraduate Medical Journal
|March 16, 2007
PubMed
Abstract

Insights

Cerebral malaria affects children beyond the typical under-five age group in holoendemic regions. This study reveals significant morbidity and mortality patterns in older children with cerebral malaria.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Neurology

Background:

  • Cerebral malaria is typically prevalent in children under five in holoendemic regions.
  • Recent observations indicate an increase in cerebral malaria cases among children older than five years.

Purpose of the Study:

  • To investigate the morbidity and mortality patterns of cerebral malaria.
  • To assess the changing demographics of cerebral malaria cases.

Main Methods:

  • Retrospective review of 154 cerebral malaria cases over a five-year period (1999-2003).
  • Data extracted from patient case notes at Obafemi Awolowo University Teaching Hospital Complex Ile-Ife.

Main Results:

  • Out of 5,456 admissions, 154 patients were diagnosed with cerebral malaria.
  • Patients aged 1-5 years constituted the largest group (128), with 8 cases in children over 5 years.
  • Mortality rate was 5.2% (8 deaths), and 10.3% (16 patients) experienced neurological deficits at discharge.

Conclusions:

  • Cerebral malaria remains a significant complication of malaria.
  • The disease burden of cerebral malaria is expanding beyond the under-five population.

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