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[Base excess. Parameter with exceptional clinical significance].

W Schaffartzik1

  • 1Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Unfallkrankenhaus Berlin, Warener Strasse 7, 12683 Berlin, Deutschland. Walter.Schaffartzik@ukb.de

Der Anaesthesist
|March 16, 2007
PubMed
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Base excess (BE) is crucial for assessing acid-base status and patient mortality risk, especially in critical care. Understanding BE

Area of Science:

  • Clinical chemistry
  • Medical diagnostics
  • Acid-base balance

Context:

  • Base excess (BE) is increasingly vital for evaluating patient acid-base status and predicting mortality risk in trauma patients.
  • BE calculation integrates pH, pCO(2), hemoglobin, and oxygen saturation (sO(2)) for consistent measurement across blood sample types.
  • BE and lactate concentration (cLac) are key indicators for diagnosing critically ill patients.

Purpose:

  • To highlight the clinical significance of Base Excess (BE) in patient assessment.
  • To explain the calculation and utility of BE, particularly its relationship with lactate levels.
  • To emphasize the need for manufacturers to provide infusion solution data regarding their impact on BE.

Summary:

  • Base excess (BE) is a key parameter for acid-base status and mortality risk assessment in critically ill patients.

Related Experiment Videos

  • BE calculation, using pH, pCO(2), hemoglobin, and sO(2), provides a standardized measure.
  • The correlation between BE and lactate concentration (cLac) aids in diagnosing and managing patients, with deviations suggesting specific interventions like bicarbonate or lactate-containing infusions.

    • Impact:

    • BE aids in identifying mortality risk in patients with multiple injuries.
    • The relationship between BE and cLac changes can indicate therapeutic interventions such as bicarbonate or lactate infusions.
    • Standardized reporting of infusion solution effects on BE would enhance clinical treatment decisions for critically ill patients.