Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 16, 2026

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection
12:57

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection

Published on: October 13, 2017

Autometallographic tracing of quantum dots.

M Stoltenberg1, A Larsen, P Doering

  • 1Department of Neurobiology, Institute of Anatomy, University of Aarhus, Aarhus C, Denmark. ms@neuro.au.dk

Histology and Histopathology
|March 16, 2007
PubMed
Summary

Semiconductor quantum dots (QDs) and gold nanoparticles can be visualized in tissues and cells using autometallographic (AMG) silver enhancement. This highly sensitive method allows tracking of marked cells and detection of even sub-nanometer QDs.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immature teratoma of the ovary in children and adolescents: A multi-institutional study of characteristics and management.

Gynecologic oncology·2026
Same author

Immature teratoma of the ovary with microscopic yolk sac tumor in children and adolescents: A multi-institutional study.

Gynecologic oncology·2026
Same author

Is There More than One Erythropoietin Receptor? Can the Hematopoietic Effects of EPO Be Dissociated from the Organ-Protective Effects by Carbamylated Erythropoietin?: Derivatives of erythropoietin that are tissue protective but not erythropoietic. Science 305: 239-242, 2004.

Journal of the American Society of Nephrology : JASN·2023
Same author

Uptake of antenatal care in high HIV-prevalence settings: Results from three population-based surveys in South Africa.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde·2020
Same author

Beaver effects on macroinvertebrate assemblages in two streams with contrasting morphology.

The Science of the total environment·2020
Same author

Time to Diagnosis and Treatment with Palliative Radiotherapy among Inuit Patients with Cancer from the Arctic Territory of Nunavut, Canada.

Clinical oncology (Royal College of Radiologists (Great Britain))·2019

Area of Science:

  • Biotechnology
  • Nanotechnology
  • Cell Biology

Background:

  • Semiconductor quantum dots (QDs) offer unique optical properties for bioimaging.
  • Visualizing nanoscale materials in biological samples presents significant technical challenges.
  • Autometallographic (AMG) silver enhancement is a known technique for amplifying signals.

Purpose of the Study:

  • To demonstrate the visualization of semiconductor quantum dots (QDs) in tissue sections using autometallographic (AMG) silver enhancement.
  • To show how AMG-enhanceable gold nanoparticles can track isolated cells in various biological contexts.
  • To highlight the sensitivity of the AMG method for detecting nanoscale materials.

Main Methods:

  • Application of autometallographic (AMG) silver enhancement to tissue sections containing semiconductor quantum dots (QDs).

More Related Videos

Production and Targeting of Monovalent Quantum Dots
10:16

Production and Targeting of Monovalent Quantum Dots

Published on: October 23, 2014

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles
11:16

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles

Published on: August 7, 2016

Related Experiment Videos

Last Updated: Jul 16, 2026

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection
12:57

Resonance Fluorescence of an InGaAs Quantum Dot in a Planar Cavity Using Orthogonal Excitation and Detection

Published on: October 13, 2017

Production and Targeting of Monovalent Quantum Dots
10:16

Production and Targeting of Monovalent Quantum Dots

Published on: October 23, 2014

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles
11:16

Correlative Light- and Electron Microscopy Using Quantum Dot Nanoparticles

Published on: August 7, 2016

  • Introduction of AMG-enhanceable gold nanoparticles into isolated cells for subsequent tracking.
  • Microscopical analysis (LM and EM) of AMG-enhanced samples.

    • Main Results:

    • Semiconductor quantum dots (QDs) were successfully visualized in tissue sections via AMG silver enhancement.
    • AMG-enhanceable gold nanoparticles enabled the tracking of isolated cells in organisms and cell cultures.
    • The AMG method proved highly sensitive, detecting QDs smaller than one nanometer.

    Conclusions:

    • Autometallographic (AMG) silver enhancement is an effective and sensitive technique for visualizing semiconductor quantum dots in biological tissues.
    • This method facilitates the study of cellular dynamics and fate by enabling the tracking of nanoparticle-labeled cells.
    • The high sensitivity of AMG allows for the detection of very small nanomaterials at both light and electron microscopy levels.