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Ciprofloxacin-induced palatal tremor.
Yuk-Fai Cheung1, Winnie Wing-Yin Wong, Kwok-Wing Tang
1Department of Medicine, Neurology Division, Queen Elizabeth Hospital, Hong Kong, China. cyfz02@ha.org.hk
Ciprofloxacin treatment can cause palatal tremor, characterized by rhythmic movements of the palate, face, and trunk. Symptoms resolved after discontinuing the antibiotic and starting sodium valproate.
Area of Science:
- Neurology
- Pharmacology
Background:
- Antibiotic-induced movement disorders are rare but significant adverse effects.
- Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic with known neurological side effects.
Observation:
- An 84-year-old male patient developed palatal tremor during ciprofloxacin therapy.
- The tremor involved rhythmic movements of the soft palate, face, and trunk.
- Symptoms emerged during antibiotic treatment.
Findings:
- This case represents the first documented instance of palatal tremor secondary to ciprofloxacin use.
- Discontinuation of ciprofloxacin led to symptom resolution.
- Co-administration of sodium valproate was part of the treatment regimen.
Implications:
- Clinicians should consider ciprofloxacin as a potential cause of palatal tremor.
- Awareness of this adverse drug reaction is crucial for patient safety.
- Further research may elucidate the mechanisms of fluoroquinolone-induced movement disorders.
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