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Related Concept Videos

Allergic Reactions02:06

Allergic Reactions

Overview
Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
Allergic Drug Reactions01:27

Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Hypersensitivities01:30

Hypersensitivities

Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Drug Toxicity: Allergic Reactions01:30

Drug Toxicity: Allergic Reactions

Drug-related allergies are immune-mediated responses triggered by the administration of pharmacological agents. These hypersensitivity reactions are classified based on the immune mechanisms involved. The four primary types—Type I, II, III, and IV—are mediated by different immunological pathways and exhibit distinct clinical manifestations.Type I Hypersensitivity/ IgE-Mediated Reactions: Immunoglobulin E (IgE) immediately mediates Type I hypersensitivity reactions. Upon initial exposure to a...
Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...

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Related Experiment Video

Updated: Jul 16, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
08:47

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

[Oral allergy syndrome--problem].

Graiyna Doroszewska1, Piotr Winiarski, Zbigniew Bartuzi

  • 1Oddzial Laryngologii Wojewódzkiego Szpitala, im. J. Biziela w Bydgoszczy.

Otolaryngologia Polska = the Polish Otolaryngology
|March 16, 2007
PubMed
Summary

Oral Allergy Syndrome (OAS), a pollen-food cross-reactive reaction, remains incompletely understood. Early recognition and management are crucial, especially for severe reactions like throat swelling and anaphylaxis.

Area of Science:

  • Immunology
  • Allergology
  • Otolaryngology

Context:

  • Oral Allergy Syndrome (OAS) describes pollen-food cross-reactivity, first named in 1987.
  • Despite its prevalence, knowledge gaps persist among non-allergists, including laryngologists.
  • Understanding OAS is vital due to potential severe reactions like pharyngeal and laryngeal swelling, and anaphylaxis.

Purpose:

  • To synthesize current knowledge on Oral Allergy Syndrome.
  • To provide insights relevant to laryngological practice regarding OAS.
  • To emphasize the importance of recognizing and managing OAS, particularly severe manifestations.

Summary:

  • OAS involves cross-reactions between pollens and foods, often presenting with localized oral symptoms (irritation, swelling).

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A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
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Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

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Last Updated: Jul 16, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber
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Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

Published on: March 3, 2023

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma
06:34

A Component-resolved Diagnostic Approach for a Study on Grass Pollen Allergens in Chinese Southerners with Allergic Rhinitis and/or Asthma

Published on: June 4, 2017

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay
06:08

Immunofluorescent Labeling in Nasal Mucosa Tissue Sections of Allergic Rhinitis Rats via Multicolor Immunoassay

Published on: September 22, 2023

  • While typically mild and transient, these symptoms can escalate to systemic reactions including urticaria, asthma, abdominal pain, and anaphylaxis.
  • Diagnosis relies on patient history and RAST testing.
  • Management strategies encompass food avoidance, medication, and specific immunotherapy.

    • Impact:

    • Enhances understanding of OAS among specialists beyond allergology.
    • Improves diagnostic and management strategies in laryngological practice for food-induced hypersensitivity.
    • Raises awareness among pollen-allergic individuals about potential fruit and vegetable hypersensitivity.