Related Experiment Video
Updated: Jul 16, 2026

Electrophoretic Delivery of γ-aminobutyric Acid (GABA) into Epileptic Focus Prevents Seizures in Mice
Published on: May 16, 2019
PET tracer technology for monitoring focal epilepsies
1National Hospital for Neurology and Neurosurgery, Queen Square, London, UK. mkoepp@ion.ucl.ac.uk
Abstract:
Studies using positron emission tomography (PET) have advanced our pathophysiological and biochemical understanding of focal and generalized epilepsies. H(2) (15)O PET allows quantification of cerebral blood flow and (18)F-fluorodeoxyglucose-PET quantification of cerebral glucose metabolism. Neurotransmitters are directly responsible for modulating synaptic activity and newer PET tracers can provide information about synaptic activity and specific ligand-receptor relationships, which are important for epileptogenesis and the spread of epileptic activity.
