Putative cancer stem cells in cutaneous malignancies
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Updated: Jul 16, 2026

Patient Derived Cell Culture and Isolation of CD133+ Putative Cancer Stem Cells from Melanoma
Published on: March 13, 2013
Maria R Kamstrup1, Robert Gniadecki, Gunhild L Skovgaard
1Department of Dermatology, University of Copenhagen, Bispebjerg Hospital, Copenhagen, Denmark. mk43@bbh.hosp.dk
Abstract:
Recent experimental data offer convincing evidence for the existence of cancer stem cells in leukaemia, brain tumors and breast cancer. These cells are responsible for the maintenance of tumor growth and relapses after cytoreductive treatments. This paper provides a brief overview of current data supporting the idea of cancer stem cells in the pathogenesis of cutaneous malignancies, including skin carcinoma, malignant melanoma and cutaneous T-cell lymphoma. The characterization of putative cancer stem cells is important to develop new therapies selectively targeting these cells.
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