Related Experiment Video
Updated: Jul 16, 2026

Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery
Published on: June 2, 2022
Childhood obesity and anesthetic morbidity
1Driscoll Children's Hospital, Department of Anesthesiology, University of Texas, Medical Branch Galveston Corpus Christi, TX, USA.
Insights
Obese children undergoing dental surgery experienced a slight increase in minor respiratory complications during anesthesia. Inhalation induction proved safe for this group, with no associated adverse events observed.
Area of Science:
- Anesthesiology
- Pediatric Medicine
- Public Health
Background:
- Obesity is a growing concern in pediatric populations presenting for anesthesia.
- The incidence of anesthesia-related complications in obese children is not well-established.
- Obese adults often face anesthetic challenges, but data for children are limited.
Purpose of the Study:
- To compare anesthetic-related complications in obese versus nonobese children undergoing dental surgery.
- To evaluate the safety and efficacy of different anesthetic induction methods in pediatric obesity.
- To identify specific risks associated with general anesthesia in obese pediatric patients.
Main Methods:
- Retrospective chart review of 1133 children (ASA physical status I and II) under 12 years old undergoing dental outpatient procedures.
- Calculation of Body Mass Index (BMI) to identify obese children based on international normative data.
- Documentation of anesthetic induction methods and perioperative complications.
Main Results:
- 100 obese and 1033 nonobese children were identified; groups were demographically comparable.
- Inhalation induction was the predominant method (99% obese, 99.7% nonobese) with a low overall complication rate.
- Obese children had a higher incidence of minor respiratory complications, including intraoperative oxygen desaturation (2% vs 0.19%) and unexpected overnight hospitalization (2% vs 0.19%).
Conclusions:
- Obese children undergoing anesthesia for dental procedures showed a modest increase in minor respiratory complications.
- Inhalation induction was not linked to an increased risk of adverse events in this pediatric obese population.
- The findings suggest that while minor respiratory issues are slightly more common, inhalation anesthesia is a viable option for obese children.
Background:
Obesity is present in a significant proportion of children presenting for anesthesia. Although it is perceived that obese adults have more frequent complications, the incidence of complications in obese children is unknown. Because of anticipated difficulties with mask ventilation, anesthesia is most frequently induced intravenously in obese adults, whereas inhalation induction is usually preferred in uncooperative children with few visible veins. The purpose of this study was to examine and compare anesthetic related complications in obese children undergoing dental surgery with a similar group of nonobese individuals.
Methods:
The charts of 1133 American Society of Anesthesiology (ASA) physical status I and II children less than 12 years old who underwent general anesthesia for dental outpatient procedures in 2003 were retrospectively examined for patient height, weight, preoperative evaluation, anesthetic course and postoperative course. Body mass index was calculated and compared with international normative data to identify those children who were obese. Method of induction and perioperative complications were noted.
Results:
A total of 100 obese and 1033 nonobese children were identified. Demographically the two groups were comparable. Inhalation induction was used in the vast majority of obese (99%) and nonobese (99.7%) patients. Overall complication rate was low. Minor respiratory complications were more frequently noted in the obese group. These consisted primarily of a higher incidence of intraoperative oxygen desaturation (2% vs 0.19%) and higher requirements for unexpected overnight hospitalization (2% vs 0.19%). The only complication related directly to inhalation induction was noted in a nonobese child who vomited and aspirated on induction.
Conclusions:
Our study demonstrated a small increase in minor respiratory complications in obese children who underwent anesthesia. Inhalation induction was not associated with an increase in adverse events in this population.
Related Concept Videos
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Parenteral Anesthetics: Overview
Drug Dosing: Obese Patients
Pyloric Obstruction
Inhalational Anesthetics: Overview
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution