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Related Concept Videos

Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).
Applications Of NMR In Biology01:25

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics  for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.
The...

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Related Experiment Video

Updated: Jul 16, 2026

Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line
08:23

Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line

Published on: August 9, 2014

RNA interference: a tool for querying nervous system function and an emerging therapy.

Beverly L Davidson1, Ryan L Boudreau

  • 1Department of Internal Medicine, University of Iowa, Iowa City, IA 52242, USA. beverly-davidson@uiowa.edu

Neuron
|March 16, 2007
PubMed
Summary

RNA interference (RNAi) is a powerful gene silencing tool. Recent advances show its potential in neuroscience for understanding neuronal function and treating neurological disorders.

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Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry
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Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry

Published on: September 27, 2020

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Last Updated: Jul 16, 2026

Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line
08:23

Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line

Published on: August 9, 2014

Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry
10:58

Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry

Published on: September 27, 2020

Area of Science:

  • Molecular Biology
  • Neuroscience

Background:

  • RNA interference (RNAi) is a biological process for gene silencing.
  • MicroRNA (miRNA) biogenesis and gene suppression mechanisms are increasingly understood.
  • RNAi technologies are utilized as biological tools across various systems.

Purpose of the Study:

  • To review the current state of RNA interference (RNAi) in neuroscience.
  • To highlight the utility of RNAi for neuroscientists.
  • To discuss advances in inhibitory RNA delivery to the nervous system.

Main Methods:

  • Review of current literature on RNAi in neuroscience.
  • Summary of progress in understanding miRNA biogenesis and function.
  • Analysis of RNAi applications in neurological disease models.

Main Results:

  • Significant progress has been made in delivering inhibitory RNAs to the nervous system.
  • Endogenous miRNAs play roles in neuronal development and function.
  • RNAi demonstrates therapeutic efficacy in mouse models of human neurological conditions.

Conclusions:

  • RNA interference is a rapidly advancing field with significant implications for neuroscience.
  • RNAi holds promise as a therapeutic strategy for neurological disorders.
  • Further research is needed to fully leverage RNAi in neurobiology and medicine.