Covalent modification of DNA regulates memory formation

Courtney A Miller1, J David Sweatt

  • 1Department of Neurobiology and the Evelyn F. McKnight Brain Institute,University of Alabama at Birmingham, Birmingham, AL 35294, USA.

Neuron
|March 16, 2007
PubMed
Summary

DNA methylation, a key epigenetic mechanism, dynamically regulates gene expression in the adult brain. This study shows DNA methyltransferases (DNMTs) are crucial for memory formation and consolidation in rats.

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