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Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms
Published on: August 11, 2015
Intracranial infectious aneurysm: presentation, management and outcome
Sudheeran Kannoth1, Rajesh Iyer, Sanjeev V Thomas
1Department of Neurology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
Journal of the Neurological Sciences
|March 16, 2007
Summary
Intracranial infectious aneurysms (IA) present differently based on infection source. Local infections like meningitis lead to proximal IAs, while systemic infections favor distal carotid IAs, impacting mortality.
Area of Science:
- Neurology
- Infectious Diseases
- Vascular Surgery
Background:
- Intracranial infectious aneurysms (IA) are rare but life-threatening vascular conditions.
- Distinguishing IA clinical profiles based on infection source is crucial for effective management.
Purpose of the Study:
- To compare the clinical characteristics of intracranial infectious aneurysms (IA) arising from systemic infections (e.g., infective endocarditis) versus local infections (e.g., meningitis).
Main Methods:
- A retrospective analysis of 25 patients with 29 intracranial infectious aneurysms (IA) treated between 1976 and 2003.
- Identification of prognostic factors and comparison of IA clinical profiles based on infection source.
Main Results:
- Headache and fever were common presenting symptoms; intracerebral hemorrhage was more frequent than subarachnoid hemorrhage.
- IAs associated with meningitis were predominantly proximal, while those linked to cardiac disease were distal and involved the carotid territory (p=0.013).
- Overall mortality was 32%, with higher rates observed in cases of meningitis, fungal infections, and vertebrobasilar involvement.
Conclusions:
- Intracranial infectious aneurysms (IA) associated with local infections like meningitis exhibit distinct clinical profiles compared to those from systemic infections like infective endocarditis.
- Understanding these differences is vital for improving diagnostic accuracy and therapeutic strategies for IA.
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