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Quorum-sensing blockade as a strategy for enhancing host defences against bacterial pathogens

Thomas Bjarnsholt1, Michael Givskov

  • 1BioScience and Technology, bldg 227, BioCentrum, Technical University of Denmark, 2800 Lyngby, Denmark.

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
|March 16, 2007
PubMed
Summary

Targeting bacterial pathogenicity via quorum sensing (QS) offers a novel strategy against antibiotic resistance. Blocking QS, rather than bacterial growth, may enhance host defenses and combat multi-drug resistant infections.

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