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Related Experiment Videos

Ectopic intrathyroidal nonfunctioning parathyroid cyst.

Marco Capezzone1, Eugenia Morabito, Pasquale Bellitti

  • 1Unit of Endocrinology, Hospital of Tinchi-Pisticci, Matera, Italy.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
|March 16, 2007
PubMed
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This case report details a rare ectopic intrathyroidal parathyroid cyst (PC) incidentally found alongside papillary microcarcinoma. The parathyroid cyst resolved after fine-needle aspiration but recurred, necessitating thyroidectomy.

Area of Science:

  • Endocrinology
  • Surgical Pathology
  • Diagnostic Imaging

Background:

  • Ectopic parathyroid cysts (PCs) are rare, often asymptomatic, and can be associated with thyroid nodules.
  • Multinodular goiter is a common thyroid condition that can present diagnostic challenges.

Observation:

  • A 29-year-old woman with multinodular goiter presented with a cystic lesion in the thyroid.
  • Fine-needle aspiration biopsy of the cyst revealed high parathyroid hormone levels, confirming an intrathyroidal parathyroid cyst.
  • The cyst resolved post-biopsy but recurred, leading to near-total thyroidectomy.

Findings:

  • Histologic examination confirmed the intrathyroidal parathyroid cyst and, incidentally, a 6 mm papillary microcarcinoma in the contralateral thyroid lobe.
  • The parathyroid hormone and calcium levels were normal, indicating a nonfunctioning cyst.

Related Experiment Videos

  • This is the first reported association of an intrathyroidal PC with papillary microcarcinoma.

    • Implications:

    • The co-occurrence of intrathyroidal parathyroid cysts and papillary microcarcinoma may be coincidental, given the high prevalence of occult papillary microcarcinoma.
    • This case highlights the importance of thorough evaluation of thyroid nodules and cystic lesions, even when seemingly benign.
    • Accurate diagnosis and management are crucial for rare ectopic parathyroid lesions within the thyroid gland.