Zoonoses in the Mediterranean region

Aristarco Seimenis1, Daniela Morelli, Adriano Mantovani

  • 1WHO Mediterranean Zoonoses Control Centre, 24 Stournari St., 10682 Athens, Greece. mzcc@ath.forthnet.gr

Insights

The Mediterranean and Middle East Region (MME) is a key area for zoonotic diseases, with both traditional and globalized urban patterns influencing their spread and impact. Understanding these zoonoses is crucial for public health initiatives.

Area of Science:

  • Veterinary Public Health
  • Epidemiology
  • Infectious Diseases

Background:

  • The Mediterranean and Middle East Region (MME) is historically significant for zoonotic disease development and concentration.
  • Emergence of an urbanized zoonotic pattern, influenced by globalization, coexists with the classical Mediterranean pattern.
  • Both patterns present unique characteristics impacting zoonotic life cycles and societal effects.

Purpose of the Study:

  • To discuss the features of the most relevant zoonoses in the MME.
  • To highlight the co-existing epidemiological patterns of zoonoses in the region.
  • To inform about public health initiatives for zoonoses control.

Main Methods:

  • Review and discussion of key zoonotic diseases prevalent in the MME.
  • Analysis of epidemiological patterns (Mediterranean and urbanized).
  • Overview of the World Health Organization's (WHO) Mediterranean Zoonoses Control Centre (MZCC) activities.

Main Results:

  • Brucellosis, rabies, cystic echinococcosis, leishmaniasis, and food-borne zoonoses are identified as highly relevant in the MME.
  • The interplay between traditional and urbanized zoonotic patterns complicates disease management.
  • The MZCC, established in 1979, coordinates regional efforts.

Conclusions:

  • The MME faces complex zoonotic challenges due to distinct epidemiological patterns.
  • Targeted control strategies are necessary to address prevalent zoonoses like brucellosis and rabies.
  • International collaboration, exemplified by the MZCC, is vital for managing zoonotic diseases in the region.

Related Concept Videos

Rabies01:28

Rabies

Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Transmission of Pathogens01:24

Transmission of Pathogens

Pathogens spread from their reservoirs to susceptible hosts through three main routes: contact transmission, vehicle transmission, and vector transmission. Each route involves distinct mechanisms of transfer.Contact TransmissionThis category includes direct contact, indirect contact, and droplet transmission:Direct contact involves immediate physical interaction between individuals—such as a handshake—which can spread pathogens like Streptococcus pyogenes, the bacterium responsible for...
Reservoir of Infection01:30

Reservoir of Infection

Infectious diseases arise from intricate interactions between pathogens and their reservoirs. A reservoir of infection refers to the natural habitat where a pathogen lives, grows, and multiplies, serving as a continual source of infection. Reservoirs are broadly classified as either living or nonliving, and each plays a unique role in disease transmission, significantly influencing public health interventions and control strategies.Humans act as reservoirs for a wide array of pathogens,...
Bacterial Phylum Spirochaetes01:30

Bacterial Phylum Spirochaetes

Spirochetes, unique bacteria in the phylum Spirochaetes, are gram-negative, motile, tightly coiled, slender, and flexible. They inhabit aquatic sediments and animals, with some causing diseases like syphilis. Spirochetes are classified into eight genera based on habitat, pathogenicity, phylogeny, and characteristics.Their distinctive motility arises from endoflagella, located within the cell’s periplasm. These endoflagella anchor at the cell poles and extend along the cell length, encased by a...
Plague01:24

Plague

Plague is a highly virulent zoonotic disease caused by Yersinia pestis, a Gram-negative, facultatively anaerobic coccobacillus. This pathogen primarily circulates among rodent populations and is transmitted to humans through the bite of infected fleas. Additional transmission routes include direct contact with infected animal tissue or inhalation of respiratory droplets from individuals with pneumonic plague. These multiple transmission pathways highlight the bacterium’s potential for rapid...