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Updated: Jul 16, 2026

A Strategy to Identify de Novo Mutations in Common Disorders such as Autism and Schizophrenia
Published on: June 15, 2011
[Genetics of schizophrenia: advances in the study of candidate genes]
Adriana Pacheco1, Henriette Raventós
1CIBM, Universidad de Costa Rica, 2060 San José, Costa Rica.
Abstract:
Schizophrenia is one of the most severe mental disorders that affect 1% of the population worldwide. It is clear that both genetic and environmental factors participate in its etiology. Nonetheless, the effort to identify susceptibility genes has been difficult and there are no unequivocal findings until now. Notwithstanding this, during the last couple of years, a group of candidate genes has been identified because of their possible role in the physiopathology or by association and linkage studies. In this article, the role of these genes is summarized as well as the results of the studies conducted in Costa Rica by our group.
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