Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A noninvasive protocol for anterior temporal lobectomy.

M R Sperling1, M J O'Connor, A J Saykin

  • 1Comprehensive Epilepsy Center, Graduate Hospital, Philadelphia, PA 19146.

Neurology
|February 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Blood acid/base balance in poultry: Dietary, environmental, and physiological determinants and emerging diagnostic opportunities.

Poultry science·2026
Same author

Coccidiosis in chickens: From temporal patterns of Lesion development and Oocyst shedding to predictive modeling.

Poultry science·2025
Same author

Dynamic responses of blood metabolites to nutrient depletion and repletion in broiler chicken nutrition.

Poultry science·2024
Same author

Assessment of factual recall and higher-order cognitive domains in an open-book medical school examination.

Advances in health sciences education : theory and practice·2021
Same author

Editorial: How Will Aducanumab Approval Impact AD Research?

The journal of prevention of Alzheimer's disease·2021
Same author

Medical care disruptions during the first six months of the COVID-19 pandemic: the experience of older breast cancer survivors.

Breast cancer research and treatment·2021

This study presents an objective algorithm for selecting epilepsy surgery candidates, achieving an 80% seizure-free rate after temporal lobectomy. The protocol effectively identifies suitable patients for epilepsy surgery without invasive monitoring.

Area of Science:

  • Neurosurgery
  • Epilepsy Management
  • Neurology

Background:

  • Temporal lobectomy is a common surgical intervention for refractory epilepsy.
  • Accurate patient selection is crucial for successful surgical outcomes.
  • Current selection protocols may benefit from objective, non-invasive methods.

Purpose of the Study:

  • To evaluate a protocol for selecting candidates for temporal lobectomy using objective tests.
  • To determine the efficacy of a standardized algorithm in identifying suitable surgical candidates.
  • To assess seizure outcomes in patients undergoing temporal lobectomy based on protocol criteria.

Main Methods:

  • A standard battery of objective tests was employed to assess potential candidates.
  • An algorithm, assigning importance levels to each test, was used for candidate selection.

Related Experiment Videos

  • Fifty-one patients meeting protocol criteria underwent anterior temporal lobectomy.

    • Main Results:

    • 80% of patients achieved seizure freedom post-surgery.
    • 12% experienced reduced seizure frequency (less than 3 per year or nocturnal only).
    • 8% demonstrated over 80% reduction in seizure frequency.

    Conclusions:

    • The developed objective protocol is effective in selecting candidates for temporal lobectomy.
    • The algorithm aids in identifying patients likely to benefit from epilepsy surgery.
    • This non-invasive approach can improve surgical candidate selection and outcomes.