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Updated: Jul 16, 2026

Laparoscopic Radical Gastrectomy for Remnant Gastric Cancer
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Laparoscopic total gastrectomy for Ménétrier's disease.

Caroline Sanchez1, Fred Brody, Edward Pucci

  • 1Department of General Surgery, Division of Gastroenterology and Liver Disease, The George Washington University Medical Center, Washington, DC 20037, USA.

Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
|March 17, 2007
PubMed
Summary

Ménétrier

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Area of Science:

  • Gastroenterology
  • Surgical Oncology

Background:

  • Ménétrier's disease is a rare condition characterized by enlarged gastric folds.
  • Typically managed non-surgically with supportive care.

Observation:

  • A 41-year-old male with HIV and hepatitis B presented with severe gastrointestinal symptoms.
  • Imaging revealed diffuse gastric thickening; endoscopy showed chronic gastritis and enlarged folds without H. pylori.

Findings:

  • Laparoscopic biopsy confirmed foveolar hyperplasia consistent with Ménétrier's disease.
  • Despite initial conservative management, the patient developed worsening symptoms and lower GI bleeding.
  • A laparoscopic total gastrectomy was successfully performed, leading to symptom resolution.

Implications:

  • This case highlights the potential need for surgical intervention in refractory Ménétrier's disease.
  • Minimally invasive surgical techniques can be safely employed for complex cases.
  • Successful gastrectomy offers a viable treatment option for severe, symptomatic Ménétrier's disease.

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