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How cost-effective is screening for abdominal aortic aneurysms?

L G Kim1, S G Thompson, A H Briggs

  • 1MRC Biostatistics Unit, Institute of Public Health, Robinson Way, Cambridge CB2 2SR, UK. lois.kim@mrc-bsu.cam.ac.uk

Journal of Medical Screening
|March 17, 2007
PubMed
Summary

Screening for abdominal aortic aneurysms in men is highly cost-effective over 30 years, offering significant value for a national screening program. This approach saves lives and improves health outcomes for the UK male population.

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Area of Science:

  • Health economics
  • Preventive medicine
  • Vascular surgery

Background:

  • Abdominal aortic aneurysm (AAA) is a serious condition requiring effective screening strategies.
  • Estimating the long-term economic impact of AAA screening is crucial for public health policy.

Purpose of the Study:

  • To determine the long-term cost-effectiveness of screening men for abdominal aortic aneurysms.
  • To provide reliable economic data to support a potential national screening program in the UK.

Main Methods:

  • A 30-year Markov health economic decision model was developed.
  • Model parameters were derived from patient data from the UK Multi-centre Aneurysm Screening Study.
  • Probabilistic sensitivity analysis was used to address parameter uncertainty.

Main Results:

  • Screening is highly cost-effective over 30 years, costing £2320 per life-year gained.
  • The cost per quality-adjusted life-year gained was £2970.
  • The estimated annual cost for screening the UK male population is £19 million.

Conclusions:

  • Long-term screening for abdominal aortic aneurysms in men is highly cost-effective.
  • The findings support the implementation of a national screening program in the UK.