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Ovarian endomyometrioma with atypias: description of a case
Gian Franco Zannoni1, Valerio Gaetano Vellone, Guido Fadda
1Department of Pathology, Faculty of Medicine Agostino Gemelli, Catholic University, Rome, Italy. gfzannoni@rm.unicatt.it
Objective:
To report on a patient with endomyometrioma with atypias and to review the literature.
Design:
Case report and literature review.
Setting:
Clinical and pathologic.
Patient(S):
A 33-year-old nulliparous woman with right flank pain and infertility.
Main Outcome Measure(S):
Accuracy of diagnosis, hypotheses on endomyometrioma pathogenesis.
Result(S):
A 33-year-old woman with an 8-cm right ovarian mass is reported. An extensive review of the literature on this rare disease revealed only nine well-documented cases with different views on pathogenesis. The final diagnosis required an accurate sampling and the aid of immunohistochemical markers.
Conclusion(S):
Endomyometrioma is an extremely rare entity. None of the previous cases showed cytologic atypias. The finding of atypias, in analogy with endometriosis, suggests the müllerian metaplastic theory.
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