Unstable angina patients treated with percutaneous coronary intervention in the new millennium: what characterizes
Daniele da Silva Peixoto1, Luiz Fernando Leite Tanajura, Amanda G M R Sousa
1Instituto Dante Pazzanese de Cardiologia, São Paulo, SP, Brazil.
Insights
Unstable angina patients treated with percutaneous coronary intervention (PCI) frequently had hypertension and hypercholesterolemia. Complex lesions in native vessels were common, with stenting being the primary intervention method.
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Unstable angina (UA) is a critical manifestation of coronary artery disease (CAD).
- Percutaneous coronary intervention (PCI) is a key treatment modality for UA.
- Understanding patient profiles and treatment patterns is crucial for optimizing care.
Purpose of the Study:
- To characterize the clinical and angiographic features of unstable angina patients undergoing PCI.
- To analyze treatment strategies and outcomes in this patient cohort.
Main Methods:
- Retrospective analysis of 1413 consecutive patients undergoing PCI for unstable angina between 2002-2004.
- Data extracted from a computerized database without specific inclusion/exclusion criteria.
Main Results:
- Common risk factors included systemic arterial hypertension (74%) and hypercholesterolemia (65%).
- Multivessel disease was present in 42% of patients, with a high proportion of complex B2/C lesions in native vessels.
- Clopidogrel (51%) and bare-metal stents (67%) were frequently used.
Conclusions:
- Subgroups IIB and IIIB lesions constituted the majority (76%) of treated lesions.
- Clopidogrel was the predominant antithrombotic agent, and stenting was the primary intervention.
- The findings highlight the prevalence of multivessel CAD and complex lesions in UA patients managed with PCI.
Objective:
To identify clinical and angiographic profiles of patients with unstable angina seen at a tertiary hospital and treated with percutaneous coronary intervention (PCI).
Methods:
Study of a consecutive series of 1413 patients, selected from a computerized database, who underwent percutaneous revascularization in the three-year period of 2002-2004. There were no inclusion/exclusion criteria.
Results:
Systemic arterial hypertension (74%) and hypercholesterolemia (65%) were the classical risk factors for coronary disease most frequently observed. Coronary artery bypass grafting and history of myocardial infarction were found in 24% and 28% of the cases, respectively. The subgroups most commonly treated were the IIB (48%) and IIIB (28%). Clopidogrel was prescribed for 51% of the patients and glycoprotein IIb/IIIa inhibitors, for 7%. Multivessel disease evidenced by coronary angiography was detected in 42% of the cases. Type B2 or C lesions were treated in 64%, 94% of which in native vessels. Restenotic lesions were dilated in 5% of the patients. All interventions were performed using coronary stents, the majority of which (67%) were standard bare-metal stents.
Conclusions:
1) Subgroups IIB and IIIB were the most frequently treated (76%); 2) Clopidogrel was the most prescribed antithrombotic agent (51%); 3) Multivessel coronary artery disease was found in 42% of the cases, most of which were complex target lesions located in native vessels; 4) Coronary stent implantation was the chief dilation technique used.
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