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Endoscopic correction of primary vesicoureteric reflux in children
1Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin, Dublin, Ireland.
Insights
Endoscopic injection of polytetrafluoroethylene (sting) successfully treated vesicoureteric reflux (VUR) in children. This minimally invasive procedure resolved VUR in 80% of patients, improving outcomes for pediatric urinary tract issues.
Area of Science:
- Pediatric Urology
- Minimally Invasive Surgery
- Renal Health
Background:
- Vesicoureteric reflux (VUR) is a common condition in children, increasing the risk of urinary tract infections and kidney damage.
- Traditional treatments for VUR can be invasive, carrying potential risks and longer recovery times.
- Endoscopic injection offers a less invasive alternative for managing pediatric VUR.
Purpose of the Study:
- To evaluate the efficacy and outcomes of endoscopic subureteric injection of polytetrafluoroethylene (STING) in children with VUR.
- To determine the success rate of the STING procedure in resolving or improving VUR.
- To assess the safety and effectiveness of this minimally invasive approach in a pediatric cohort.
Main Methods:
- Prospective follow-up of 69 children (113 ureters) treated with endoscopic subureteric polytetrafluoroethylene injection.
- A total of 105 procedures were performed on 50 female and 19 male patients.
- Vesicoureteric reflux (VUR) grading and resolution were assessed post-procedure.
Main Results:
- Thirty-eight patients achieved complete resolution of VUR.
- Sixteen patients had residual asymptomatic low-grade (I or II) VUR.
- An overall VUR improvement rate of 80% was observed in the patient cohort.
Conclusions:
- Endoscopic subureteric polytetrafluoroethylene (STING) injection is an effective treatment for pediatric vesicoureteric reflux.
- The procedure demonstrates a high success rate in resolving or improving VUR, with a favorable safety profile.
- STING offers a valuable minimally invasive option for managing VUR in children, reducing the need for more invasive surgical interventions.
Abstract:
Sixty-nine children with 113 refluxing ureters were followed prospectively after treatment with endoscopic injection of subureteric polytetrafluoroethylene (sting). The 50 female and 19 male patients had a total of 105 procedures. Thirty-eight patients have had their vesicoureteric reflux (VUR) resolved, and 16 now have asymptomatic grade I or II reflux, giving a combined patient VUR improvement rate of 80 percent.