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Imaging sequences for first pass perfusion --a review.

Peter Kellman1, Andrew E Arai

  • 1Laboratory of Cardiac Energetics, Department of Health and Human Services, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland 20892-1061, USA. kellman@nih.gov

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
|March 17, 2007
PubMed
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Cardiovascular magnetic resonance first pass perfusion imaging is advancing. Optimizing pulse sequence parameters and understanding tradeoffs are crucial for improving myocardial perfusion imaging quality and accuracy.

Area of Science:

  • Cardiovascular Magnetic Resonance Imaging
  • Medical Imaging Physics

Background:

  • Myocardial perfusion imaging (MPI) techniques are continuously evolving.
  • Cardiovascular magnetic resonance (CMR) offers advanced capabilities for assessing heart blood flow.

Purpose of the Study:

  • To review the state-of-the-art in CMR first pass perfusion pulse sequences.
  • To discuss technical issues, performance tradeoffs, and artifact mechanisms in MPI.

Main Methods:

  • Review of current CMR first pass perfusion pulse sequence designs.
  • Analysis of parameter interdependencies and their impact on image quality.
  • Discussion of multi-slice coverage schemes and artifact reduction.

Main Results:

  • Optimizing CMR perfusion protocols requires balancing various sequence parameters.

Related Experiment Videos

  • Understanding parameter tradeoffs is essential for mitigating artifacts and enhancing image quality.
  • Quantitative versus qualitative analysis impacts resolution and linearity requirements.

    • Conclusions:

    • Improving CMR first pass perfusion imaging relies on a deep understanding of pulse sequence design and parameter interactions.
    • Strategic protocol optimization is key to achieving high-quality myocardial perfusion imaging.