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Carotid cavernous fistula in CNS choriocarcinoma
Cynthia Tallent Lawton1, John Deveikis, Zoran Rumboldt
1Medical University of South Carolina School of Medicine, Medical University of South Carolina, Charleston, South Carolina, USA.
Insights
Pediatric carotid artery-cavernous sinus fistulas (CCFs) are rare, especially with central nervous system (CNS) neoplasms. A 7-year-old with CNS choriocarcinoma developed a CCF, successfully treated with embolization, suggesting a potential link.
Area of Science:
- Neuroscience
- Pediatric Oncology
- Vascular Surgery
Background:
- Carotid artery-cavernous sinus fistulas (CCFs) are uncommon in children.
- CCFs are rarely associated with central nervous system (CNS) neoplasms.
Observation:
- A 7-year-old female presented with acute proptosis and conjunctival injection.
- The patient had a known CNS choriocarcinoma.
Findings:
- Computed tomography angiography confirmed a carotid artery-cavernous sinus fistula.
- The CCF was successfully treated via endovascular embolization using detachable coils.
Implications:
- This case suggests a potential direct causal relationship between CNS choriocarcinoma and the development of CCFs in pediatric patients.
- Highlights the importance of considering vascular complications in pediatric CNS neoplasms.
Abstract:
Carotid artery-cavernous sinus fistulas (CCFs) are infrequently reported in the pediatric population, and are rarely reported in conjunction with CNS neoplasms. The authors present a 7-year-old girl with CNS choriocarcinoma who acutely developed left eye proptosis and conjunctival injection. Computed tomography angiography revealed a CCF, which was endovascularly embolized with detachable coils. There may be a direct cause-and-effect relationship between choriocarcinoma and development of CCFs.
