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Published on: May 25, 2018
Extragenital subcutaneous cellular angiofibroma. Case report.
J Fernando Val-Bernal1, Susana Rubio, M Francisca Garijo
1Department of Anatomical Pathology, Marqués de Valdecilla University Hospital, Medical Faculty, University of Cantabria, Santander, Spain. apavbj@humv.es
Summary
Cellular angiofibroma (CAF) is a rare mesenchymal neoplasm. This study details extragenital CAF cases, finding simple excision adequate and highlighting its similarity to genital CAF.
Area of Science:
- Oncology
- Pathology
- Dermatology
Background:
- Cellular angiofibroma (CAF) is a rare mesenchymal neoplasm typically found in the genital area.
- Extragenital occurrences are exceptionally uncommon, necessitating further case documentation and analysis.
Observation:
- A 38-year-old woman presented with a 3.5 cm asymptomatic subcutaneous mass in the left hypochondrium.
- The mass had enlarged over 6 months and was completely excised without recurrence at 3 months.
- Literature review identified five additional extragenital CAF cases (3 males, 2 females).
Findings:
- Extragenital CAFs occurred in adults (mean age 57 years) with varying tumor sizes (mean 9 cm).
- Locations included superficial trunk soft tissue and retroperitoneum.
- No recurrences or metastases were observed during follow-up (mean 29 months).
- Extragenital CAF shares clinicopathological features with genital CAF, differing primarily in location.
Implications:
- Simple tumorectomy is likely sufficient treatment for extragenital CAF.
- Morphological similarities suggest a close relationship between CAF and spindle cell lipoma.
- Increased awareness of extragenital CAF is warranted for accurate diagnosis and management.