Mixed Salmonella infection: case report and review of the literature

Nelun Perera1, Collin Geary, Martin Wiselka

  • 1Department of Microbiology, University Hospitals of Leicester, Leicester, UK. nelun.perera@uhl-tr.nhs.uk

Insights

A rare case of enteric fever occurred when a traveler from India had a mixed Salmonella infection. Both Salmonella Typhi and Salmonella Paratyphi A were detected in their bloodstream.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Clinical Medicine

Background:

  • Enteric fever is a systemic infection caused by Salmonella species.
  • Mixed Salmonella serotype infections are uncommon in clinical practice.

Observation:

  • A patient traveling from India presented with symptoms of enteric fever.
  • Blood cultures were performed as part of the diagnostic workup.

Findings:

  • The blood cultures revealed a mixed infection with two distinct Salmonella serotypes: Salmonella Typhi and Salmonella Paratyphi A.
  • This finding is unusual, as patients typically harbor only one serotype.

Implications:

  • Highlights the potential for co-infection with multiple Salmonella serotypes in travelers.
  • Emphasizes the importance of comprehensive microbiological investigations in diagnosing complex enteric fever cases.
  • Informs public health surveillance and clinical management strategies for Salmonella infections, particularly in endemic regions.