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Related Experiment Video

Updated: Jul 16, 2026

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Autonomously vascularized cellular constructs in tissue engineering: opening a new perspective for biomedical

E Polykandriotis1, A Arkudas, R E Horch

  • 1Department of Plastic and Hand Surgery, University of Erlangen Medical Center, Erlangen, Germany.

Journal of Cellular and Molecular Medicine
|March 21, 2007
PubMed
Summary

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Tissue engineering advances cell cultures for tissue repair. Novel in vivo vascularization models overcome limitations, enabling clinical applications for neovascularization and angiogenesis.

Area of Science:

  • Biomedical Engineering
  • Regenerative Medicine
  • Cell Biology

Background:

  • Cell cultures are vital in tissue engineering for restoring tissue function.
  • In vitro studies have extensively characterized cellular behavior and bioactive substances.
  • Recombinant DNA technology enables modulation of cellular expression profiles.

Purpose of the Study:

  • To describe recent advancements in neovascularization and angiogenesis for tissue engineering.
  • To highlight novel in vivo models inspired by reconstructive microsurgery.
  • To discuss potential clinical applications of these vascularization strategies.

Main Methods:

  • Review of latest developments in neovascularization and angiogenesis research.
  • Description of novel in vivo vascularization models utilizing vascular induction.

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Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration
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Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration

Published on: June 16, 2015

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
07:56

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

Related Experiment Videos

Last Updated: Jul 16, 2026

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids
08:22

Microfluidic Bioprinting for Engineering Vascularized Tissues and Organoids

Published on: August 11, 2017

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration
09:23

Engineering 3D Cellularized Collagen Gels for Vascular Tissue Regeneration

Published on: June 16, 2015

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo
07:56

A Full Skin Defect Model to Evaluate Vascularization of Biomaterials In Vivo

Published on: August 28, 2014

  • Exploration of reconstructive microsurgical concepts applied to tissue engineering.

    • Main Results:

    • In vivo vascularization remains a key challenge for clinical translation in tissue engineering.
    • Novel neovascularization models show promise in overcoming current limitations.
    • Axial neovascularization through vascular induction is a promising approach.

    Conclusions:

    • Neovascularization and angiogenesis are critical for successful tissue engineering.
    • In vivo models are essential for bridging the gap between laboratory findings and clinical application.
    • Future developments in vascularization hold significant potential for regenerative medicine.