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Updated: Jul 16, 2026

Isolation of Human Mesenchymal Stem Cells and their Cultivation on the Porous Bone Matrix
09:00

Isolation of Human Mesenchymal Stem Cells and their Cultivation on the Porous Bone Matrix

Published on: February 9, 2015

Human mesenchymal stem cells in contact with their environment: surface characteristics and the integrin system

Denitsa Docheva1, Cvetan Popov, Wolf Mutschler

  • 1Experimental Surgery and Regenerative Medicine, Department of Surgery,Ludwig-Maximilians-University, Munich, Germany. Denitsa.Docheva@med.uni-muenchen.de

Journal of Cellular and Molecular Medicine
|March 21, 2007
PubMed

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The extracellular matrix or ECM holds cells together to form a tissue and allows the cells within the tissue to communicate. ECM comprises proteins such as fibronectin, collagen, laminin, etc. The most abundant protein in this space is collagen. Collagen fibers are interwoven with carbohydrate-containing protein molecules called proteoglycans. ECM allows cell migration and provides a structural scaffold at cell adhesion that anchors the cell when the extracellular matrix proteins interact with...
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