Related Experiment Video
Updated: Jul 16, 2026

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
Published on: September 11, 2015
Using a dense PTFE membrane without primary closure to achieve bone and tissue regeneration
H Dexter Barber1, John Lignelli, Brian M Smith
1Department of Oral and Maxillofacial Surgery, Temple University Hospitals, Philadelphia, PA, USA. dexsurg@msn.com
Abstract:
The most common types of barrier membranes used for bone or tissue regeneration are made of expanded-polytetrafluoroethylene (e-PTFE) or resorbable materials, such as collagen. Both the e-PTFE and resorbable membranes require primary soft tissue coverage. This article explores the use of a dense-polytetrafluoroethylene (d-PTFE) membrane, which does not require primary soft tissue coverage. The advantages of d-PTFE in contrast to the other more commonly used types of barrier membranes and the clinical significance of these advantages for implant surgical and restorative treatment are discussed.

