Related Experiment Video
Updated: Jul 16, 2026

Body Composition and Metabolic Caging Analysis in High Fat Fed Mice
Published on: May 24, 2018
Sex differences in acute energy intake regulation
Brenda M Davy1, Emily L Van Walleghen, Jeb S Orr
1Department of Human Nutrition, Foods and Exercise, 221 Wallace Hall (0430), Virginia Tech, Blacksburg, VA 24061, USA. bdavy@vt.edu
Energy intake compensation after a yogurt preload was more accurate in men than women. This suggests males have better energy intake regulation, potentially protecting females from long-term weight gain.
Area of Science:
- Nutrition Science
- Human Physiology
- Behavioral Science
Background:
- Accurate energy intake regulation is crucial for maintaining energy balance.
- Sex differences in appetite regulation and energy intake compensation are not fully understood.
- Understanding these differences can inform weight management strategies.
Purpose of the Study:
- To compare energy intake compensation accuracy between males and females.
- To investigate the influence of a yogurt preload on energy intake and appetite regulation.
- To examine sex differences in hunger, satiety, and glycemic response.
Main Methods:
- Healthy young men and women participated in a controlled feeding study.
- Subjects consumed a standardized lunch meal after receiving either a yogurt preload or no preload.
- Energy intake, hunger/fullness ratings, and blood glucose levels were measured.
Main Results:
- Males demonstrated significantly more accurate energy intake compensation compared to females (86.2% vs. 73.6%).
- No sex differences were observed in subjective hunger or fullness ratings.
- Males exhibited a higher glycemic response to the preload and subsequent meal.
Conclusions:
- Energy intake regulation is more precise in males under acute feeding conditions.
- Females may have a relative inability to regulate energy intake, potentially contributing to weight gain.
- Further research is needed to explore the long-term implications of these findings.
Related Concept Videos
Regulation of Food Intake
Energy Balance
Energy Budgets and Reproductive Strategies
Metabolic States of the Body: The Postabsorptive State
Initially, glycogen stored in the liver is broken down to release glucose into the bloodstream, while glycogen in the muscles is broken down to supply glucose for energy directly within the muscle cells. As glycogen stores diminish,...
Metabolic Rate
The Basal Metabolic Rate (BMR) measures the energy expended at rest.
Several factors influence the...
Metabolic States of the Body: Fasting and Starvation

