Related Experiment Video
Updated: Jul 16, 2026

Lineage Tracing and Clonal Analysis in Developing Cerebral Cortex Using Mosaic Analysis with Double Markers (MADM)
Published on: May 8, 2020
[Theory and application of marker-assisted introgression]
Jun-Yan Bai1, Qin Zhang, Xiao-Ping Jia
1Animal Science and Technology, Henan Science and Technology University, Luoyang, China. junyanbai@163.com
Abstract:
Marker-assisted introgression (MAI) is one of the major applications of molecular information in animal breeding aiming at introgression of one or more favorable genes from a line (donor) to another (recipient), while keeping the genetic background of the recipient as much as possible. It consists of three phases. Firstly, cross donor and recipient lines to produce F1; secondly, repeated backcross the F1 individuals and the subsequent progenies with the recipient to recover its genetic background; and thirdly, intercross the backcrossed progenies to fix the introgressed genes in the population. Many factors affect the efficiency of MAI, among which the methods of foreground and background selection are very critical.
Related Concept Videos
Monohybrid Crosses
Chromosomal Theory of Inheritance
