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Updated: Jul 16, 2026

Replication of the Ordered, Nonredundant Library of Pseudomonas aeruginosa strain PA14 Transposon Insertion Mutants
Published on: May 4, 2018
[Clinical features of Pseudomonas aeruginosa infections]
J Sarlangue1, O Brissaud, C Labrèze
1Unité de néonatologie, hôpital des Enfants, CHU Pellegrin, 33076 Bordeaux, France.
Abstract:
Pseudomonas aeruginosa is a ubiquitous environmental organism usually considered as opportunistic pathogen in immunocompromised subjects. However it can produce disease in healthy children, mainly on moist body sites. Familial, community and nosocomial outbreaks of cutaneous infections have been reported. Ecthyma gangrenosum is possible without bacteremia. P. aeruginosa is also the most common cause of otitis externa in swimmers and osteomyelitis after puncture wound of the foot.
Insights
Pseudomonas aeruginosa, an opportunistic pathogen, can cause infections in healthy children, particularly on moist skin. This bacterium is linked to outbreaks and specific conditions like ecthyma gangrenosum and swimmer's ear.
Area of Science:
- Microbiology
- Infectious Diseases
- Bacteriology
Context:
- Pseudomonas aeruginosa is a common environmental bacterium.
- It is typically an opportunistic pathogen affecting immunocompromised individuals.
- However, it can cause disease in healthy children, especially on moist skin surfaces.
Purpose:
- To summarize the pathogenic potential of Pseudomonas aeruginosa.
- To highlight its role in various infections, including those in healthy populations.
- To document reported outbreaks and specific clinical manifestations.
Summary:
- Pseudomonas aeruginosa infections can occur in healthy children, often affecting moist body sites.
- Reported outbreaks include familial, community, and nosocomial settings.
- The bacterium is associated with ecthyma gangrenosum (even without bacteremia), otitis externa in swimmers, and foot osteomyelitis.
Impact:
- Increases awareness of Pseudomonas aeruginosa as a pathogen in pediatric populations.
- Underscores the importance of hygiene in preventing outbreaks.
- Provides a concise overview of P. aeruginosa-related conditions for healthcare professionals.
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