Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deep brain stimulation as a functional scalpel.

G Broggi1, A Franzini, G Tringali

  • 1Department of Neurosurgery, Istituto Nazionale Neurologico C. Besta, Milano, Italy. neurochirurgia@istituto-besta.it

Acta Neurochirurgica. Supplement
|March 21, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Relevance of Handedness in Cognitive Outcomes After Glioma Surgery in Adults: A Retrospective Study.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2026
Same author

MacroH2A1.1 as a crossroad between epigenetics, inflammation and metabolism of mesenchymal stromal cells in myelodysplastic syndromes.

Cell death & disease·2023
Same author

Incidence of Parkinson disease in North America.

NPJ Parkinson's disease·2022
Same author

Line-field confocal optical coherence tomography of psoriasis, eczema and lichen planus: a case series with histopathological correlation.

Journal of the European Academy of Dermatology and Venereology : JEADV·2022
Same author

Acute embolisms in multiple arterial districts following Ad26.COV2-S vaccine.

European review for medical and pharmacological sciences·2022
Same author

Seizure outcome after epilepsy surgery in tuberous sclerosis complex: Results and analysis of predictors from a multicenter study.

Journal of the neurological sciences·2021
Same journal

Microneurosurgical Training on Simulators: The Zurich Microsurgery Lab Experience.

Acta neurochirurgica. Supplement·2025
Same journal

Educational Impact of an Annotation System Integrated with an Exoscope for Cerebral Aneurysm Surgery: Case Description.

Acta neurochirurgica. Supplement·2025
Same journal

Artificial Intelligence and Augmented Reality in Vascular Neurosurgery.

Acta neurochirurgica. Supplement·2025
Same journal

Experiences with and Practical Implications of Using a Hybrid Operating Room.

Acta neurochirurgica. Supplement·2025
Same journal

Epidemiology and Aetiology of Cerebral Cavernous Malformations.

Acta neurochirurgica. Supplement·2025
Same journal

Novel Hemodynamic Parameters for Cerebral Ischemia in Patients with Occlusive Cerebrovascular Disease Using Dual ASL Perfusion Imaging.

Acta neurochirurgica. Supplement·2025
See all related articles

Deep brain stimulation (DBS) has been used since 1995 to treat neurological syndromes beyond Parkinson's disease. This functional scalpel shows promise for new applications due to its low complication rate and reversibility.

Area of Science:

  • Neurosurgery
  • Neurology
  • Medical Technology

Background:

  • Since 1995, the Istituto Nazionale Neurologico "Carlo Besta" (INNCB) has implanted 401 deep brain electrodes.
  • Over 200 patients remain available for follow-up and therapeutic assessment.

Purpose of the Study:

  • To review the INNCB's experience with deep brain stimulation (DBS).
  • To highlight pioneering applications of DBS beyond traditional uses.
  • To discuss the future therapeutic potential of DBS.

Main Methods:

  • Review of clinical experience with 401 deep brain electrode implantations.
  • Analysis of patient outcomes for various neurological syndromes.

Main Results:

  • DBS has been successfully applied to drug-resistant neurological syndromes including cluster headache, disruptive behavior, SUNCt, epilepsy, and tardive dystonia.

Related Experiment Videos

  • The study highlights the expansion of DBS applications beyond Parkinson's disease.

    • Conclusions:

    • Deep brain stimulation is a versatile therapeutic tool with a low complication rate and reversibility.
    • Image-guided surgery enhances DBS applicability.
    • Further expansion of DBS for novel neurological conditions is anticipated.