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Related Experiment Videos

Gastrocystoplasty in children.

E H Dykes1, P G Ransley

  • 1Department of Paediatric Urology, Hospital for Sick Children, London.

British Journal of Urology
|January 1, 1992
PubMed
Summary
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Gastrocystoplasty offers excellent outcomes for children with kidney issues, improving bladder function. Careful gastric patch sizing is crucial to manage acid secretion, especially with post-transplant medications.

Area of Science:

  • Pediatric Urology
  • Nephrology
  • Surgical Innovation

Background:

  • Children with compromised renal function often require bladder augmentation.
  • Intestinal segments have traditionally been used, but carry risks.
  • Gastrocystoplasty presents an alternative for bladder enhancement.

Purpose of the Study:

  • To evaluate the efficacy and safety of gastrocystoplasty in children with impaired kidney function.
  • To assess the physiological and biochemical outcomes of the procedure.
  • To identify potential complications and contributing factors.

Main Methods:

  • Retrospective review of 8 children undergoing gastrocystoplasty.
  • Analysis of pre- and post-operative biochemical and urodynamic parameters.

Related Experiment Videos

  • Investigation of symptomatic aciduria in select cases.

    • Main Results:

    • Excellent physiological outcomes with improved biochemical and urodynamic parameters in all patients.
    • Six patients became asymptomatic and discontinued H2-receptor blockers.
    • Two patients experienced significant acid secretion-related symptoms, linked to gastric patch size or immunosuppressive therapy.

    Conclusions:

    • Gastrocystoplasty is a highly satisfactory alternative for bladder enhancement in children with compromised renal function.
    • Gastric patch size is critical for managing acid secretion.
    • The impact of post-transplantation immunosuppressive therapy on acid production warrants further investigation.