Parapancreatic Castleman disease: contrast-enhanced sonography and CT features

Area of Science:

• Oncology
• Radiology
• Pathology

Background:

• Castleman disease is a rare lymphoproliferative disorder with three main subtypes: hyaline-vascular, plasma cell, and mixed.
• Localized Castleman disease is less common than the multicentric form.
• The para-pancreatic region is an unusual location for this condition.

Observation:

• A rare case of localized hyaline-vascular Castleman disease was identified.
• The lesion was situated in the para-pancreatic region.
• Diagnostic imaging included contrast-enhanced sonography and computed tomography (CT).

Findings:

• Contrast-enhanced sonography provided detailed visualization of the para-pancreatic lesion.
• CT imaging further elucidated the characteristics of the hyaline-vascular Castleman disease.
• The findings were consistent with a localized, rare presentation of the disease.

Implications:

• This case highlights the utility of advanced imaging in diagnosing rare Castleman disease presentations.
• Accurate diagnosis through imaging can guide appropriate management strategies.
• Understanding imaging features is crucial for differentiating Castleman disease from other pancreatic or retroperitoneal masses.