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Peritoneal mesothelioma: the role of computed tomography in diagnosis and follow up
P J Guest1, R H Reznek, D Selleslag
1Department of Diagnostic Radiology, St. Bartholomew's Hospital, London.
Abstract:
Computed tomography (CT) was performed on 15 patients with proven peritoneal mesothelioma. Eight of these patients underwent follow-up CT. It was found that a discrete and measurable mass is unusual in comparison with the common occurrence of ascites and that therefore CT has little role in quantifying the disease. Ascites is usually a prominent feature. Other features (e.g. omental infiltration) were evaluated and these could be used to assess disease progression.
Insights
Computed tomography (CT) has limited use in quantifying peritoneal mesothelioma, as discrete masses are rare. However, CT can help assess disease progression through features like ascites and omental infiltration.
Area of Science:
- Radiology
- Oncology
- Medical Imaging
Background:
- Peritoneal mesothelioma is a rare malignancy.
- Accurate staging and monitoring are crucial for patient management.
Purpose of the Study:
- To evaluate the role of computed tomography (CT) in assessing peritoneal mesothelioma.
- To determine CT's utility in disease quantification and progression monitoring.
Main Methods:
- Computed tomography (CT) scans were performed on 15 patients with proven peritoneal mesothelioma.
- Eight patients underwent follow-up CT scans for disease assessment.
Main Results:
- Discrete, measurable masses were unusual in peritoneal mesothelioma patients.
- Ascites was a prominent and common finding on CT scans.
- Omental infiltration and other features showed potential for assessing disease progression.
Conclusions:
- CT has limited value in quantifying peritoneal mesothelioma due to the rarity of discrete masses.
- CT findings, particularly ascites and omental infiltration, can aid in monitoring disease progression.
- Further research may refine CT's role in managing peritoneal mesothelioma.