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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Acne Infection01:27

Acne Infection

Acne is a multifactorial skin condition primarily affecting adolescents and young adults, with a global prevalence estimated to exceed 75% in this demographic. The condition is characterized by the formation of comedones (blackheads and whiteheads), papules, pustules, nodules, and, in severe cases, cysts, particularly in areas rich in sebaceous glands such as the face, neck, chest, and back. The pathogenesis involves increased sebum production, follicular hyperkeratinization, colonization by...
Staphylococcal Skin Infections01:29

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...
Inhalation Anthrax01:25

Inhalation Anthrax

Anthrax is a zoonotic disease caused by Bacillus anthracis, a Gram-positive, spore-forming bacterium. It primarily affects herbivorous animals but can be transmitted to humans through skin contact, ingestion, or inhalation of spores.Cutaneous anthrax, the most common form, typically results from direct contact with bacterial spores through skin abrasions and is generally less severe. Gastrointestinal anthrax results from eating undercooked or contaminated meat. It affects the mouth, throat, or...

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Related Experiment Videos

Pustular dermatitis caused by Dermatophilus congolensis.

Eileen M Burd1, Lydia A Juzych, James T Rudrik

  • 1Department of Pathology, Henry Ford Hospital, 2799 W. Grand Blvd., Detroit, MI 48202, USA. eburd1@hfhs.org

Journal of Clinical Microbiology
|March 23, 2007
PubMed
Summary

A rare case of pustular dermatitis in a teenager was linked to Dermatophilus congolensis, a bacterium typically affecting animals. This finding highlights an uncommon cause of skin infection in humans.

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Area of Science:

  • Veterinary Dermatology
  • Human Infectious Diseases
  • Microbiology

Background:

  • Dermatophilus congolensis is an actinomycete bacterium known to cause cutaneous infections in various animal species, including horses.
  • Human infections with D. congolensis are infrequently reported in medical literature.
  • Pustular dermatitis presents as a skin condition characterized by the presence of pus-filled blisters.

Observation:

  • A 15-year-old female presented with pustular dermatitis following attendance at a horseback riding camp.
  • Clinical examination revealed characteristic skin lesions consistent with pustular dermatitis.

Findings:

  • Diagnostic investigations, including gram staining and biochemical analyses, were performed on samples from the patient's lesions.
  • Whole-cell fatty acid analysis confirmed the causative agent as Dermatophilus congolensis.
  • Microbiological identification pointed to D. congolensis as the etiological agent responsible for the observed dermatitis.

Implications:

  • This case expands the known spectrum of human infections caused by Dermatophilus congolensis.
  • It underscores the importance of considering zoonotic bacterial pathogens in the differential diagnosis of unexplained dermatological conditions.
  • Further research may be warranted to understand the transmission dynamics and clinical presentation of human Dermatophilus congolensis infections.