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Findings on submillimeter MDCT are predictive of operability in chronic thromboembolic pulmonary hypertension

Jean-François Paul1, Antoine Khallil, Anne Sigal-Cinqualbre

  • 1Department of Radiology, Hôpital Marie Lannelongue, 133 ave. de la Résistance, Le Plessis-Robinson, France 92350. pauljf@ccml.fr

AJR. American Journal of Roentgenology
|March 23, 2007
PubMed
Abstract

Insights

Submillimeter 16-MDCT imaging accurately predicts the surgical plane for chronic thromboembolic pulmonary hypertension (CTEPH) endarterectomy. This non-invasive technique aids in determining patient operability and may reduce postoperative mortality.

Area of Science:

  • Cardiovascular Imaging
  • Pulmonary Hypertension Research

Background:

  • Chronic thromboembolic pulmonary hypertension (CTEPH) is a severe condition.
  • Surgical pulmonary endarterectomy is a key treatment for CTEPH.
  • Accurate preoperative assessment is crucial for surgical planning.

Purpose of the Study:

  • To evaluate the utility of 0.7-mm collimation 16-MDCT in predicting the endarterectomy plane in CTEPH patients.
  • To assess if MDCT can depict abnormal central pulmonary artery wall thickening indicative of the surgical plane.

Main Methods:

  • Retrospective review of 16-MDCT scans from 40 CTEPH patients.
  • Two blinded radiologists assessed pulmonary artery wall thickness and surgical plane presence.
  • MDCT findings were correlated with surgical outcomes.

Main Results:

  • MDCT demonstrated high sensitivity (99%), specificity (80%), and accuracy (96%) in predicting the endarterectomy plane.
  • Absence of the endarterectomy plane bilaterally correlated with increased postoperative mortality (p = 0.004).

Conclusions:

  • Submillimeter 16-MDCT is a valuable tool for predicting the endarterectomy plane in CTEPH.
  • This imaging modality can assist in determining surgical operability for CTEPH patients.
  • MDCT findings may help stratify risk and improve patient outcomes.

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