[Subepithelial keratomileusis and laser in situ keratomileusis for the correction of high myopia]

To compare the effectiveness and safety between laser subepithelial keratomileusis (LASEK) and conventional laser in-situ keratomileusis (LASIK) for high myopia.

In this prospective study, LASEK was performed in 75 eyes of 39 patients and LASIK was performed in 79 eyes of 41 patients for high myopia with a prospective clinical follow-up period.

In LASEK group, best corrected visual acuity was achieved from 1 week to 1 month postoperatively, uncorrected visual acuity was achieved to preoperative corrected visual acuity in 95.83% after 6 months since surgery, main complications include high intraocular pressure and mild corneal Haze formation; In LASIK group, uncorrected visual acuity was achieved to preoperative corrected visual acuity in 94.35% after 6 months since surgery, no corneal HAZE was examined, main complications include refractive regression and corneal epithelium ingrowth combined with flap melting.

LASIK and LASEK are all safe and effective refractive surgery for high myopia.