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Related Experiment Video

Updated: Jul 16, 2026

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Published on: March 20, 2026

Which sealant system should I use?

¹Department of Oral Health and Development, School of Clinical Dentistry, University of Sheffield, Sheffield, UK.

Evidence-Based Dentistry

|March 24, 2007

Summary

Resin-based sealants (RBS) show comparable retention rates, but light-cured resin-based sealants (LRBS) demonstrate superior long-term retention compared to fluoride-containing resin-based sealants (FRBS). Further research is needed to determine optimal clinical protocols for sealant application.

Area of Science:

Dentistry
Dental Materials Science
Evidence-Based Dentistry

Background:

This systematic review evaluated the efficacy of different resin-based sealants (RBS) and clinical protocols for their application on permanent molars.
Studies were identified through comprehensive database searches and expert consultation, focusing on randomized controlled trials comparing various RBS types and application methods.

Discussion:

The meta-analysis included 31 studies comparing different types of resin-based sealants (RBS), including light-cured (LRBS) and auto-polymerised (ARBS), as well as fluoride-containing resin-based sealants (FRBS).
While ARBS and LRBS showed similar retention rates, LRBS exhibited significantly higher retention than FRBS at 48 months.
A significant limitation was the insufficient number of high-quality studies addressing optimal clinical protocols for sealant application.

Related Experiment Videos

Last Updated: Jul 16, 2026

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Accessible Silicone Chip-to-Membrane Sealing Procedure for Flexible, Reliable Bonding

Published on: March 20, 2026

Key Insights:

Auto-polymerised resin-based sealants (ARBS) and light-cured resin-based sealants (LRBS) exhibit comparable retention rates.
Light-cured resin-based sealants (LRBS) demonstrate a significantly higher retention rate compared to fluoride-containing resin-based sealants (FRBS) over 48 months.
Current evidence is insufficient to determine the optimal clinical procedure for sealant application.

Outlook:

Future research should prioritize well-designed randomized clinical trials focusing on sealant retention.
Investigating novel enamel preparation techniques, such as air-abrasion or sono-abrasion, in conjunction with sealant application is recommended.
Standardized methodologies are needed to compare the effectiveness of different clinical protocols for resin-based sealant application.