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Published on: November 4, 2010
Clinical and therapeutic variables influencing hospitalisation for bronchiolitis in a community-based paediatric
Baha Al-Shawwa1, Nidal Al-Huniti, Miles Weinberger
1Instructor of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. balshaww@mcw.edu
Insights
Early oral corticosteroid treatment for infants with bronchiolitis may reduce hospitalisation, particularly in those with a family history of asthma or allergies, or who are RSV-negative.
Area of Science:
- Pediatrics
- Respiratory Medicine
- Clinical Research
Background:
- Bronchiolitis is a common respiratory infection in infants.
- Hospitalisation rates vary based on clinical factors and treatment interventions.
Purpose of the Study:
- To investigate the impact of clinical characteristics and treatments on infant hospitalisation for bronchiolitis in an outpatient setting.
Main Methods:
- Retrospective review of medical records for infants under two years with a first wheezing episode.
- Primary outcome: hospitalisation within ten days of outpatient evaluation.
Main Results:
- 17% of 320 infants were hospitalised; younger age, RSV positivity, and tobacco smoke exposure were linked to higher hospitalisation.
- Oral corticosteroids were associated with reduced hospitalisation in infants with a family history of asthma/allergic rhinitis and in RSV-negative infants.
Conclusions:
- Outpatient oral corticosteroid treatment may lower hospitalisation rates for bronchiolitis in specific infant subgroups.
- Identifying high-risk infants and tailoring early treatment can potentially reduce hospital admissions.
Aim:
To examine the effect of different clinical characteristics and different treatments on the hospitalisation of infants with bronchiolitis seen in an outpatient clinic setting.
Methods:
The medical records of infants under 2 years of age who presented with a first episode of wheezing over a two-year period were reviewed retrospectively. Hospitalisation within ten days of evaluation was used as the primary outcome measure.
Results:
Data from 320 patients were included. 17% were hospitalised. Age was lower in the hospitalised patients (4.9 months vs. 7.1, p<0.001). Hospitalisation was higher in RSV-positive versus RSV-negative patients (38% vs. 10%, p<0.001) and was higher in those children who had been exposed to tobacco smoke versus those who hadn't (24% vs. 12%, p<0.01). Treatment with oral corticosteroids was associated with fewer hospitalisations in those patients with a family history of asthma or allergic rhinitis (9.7% vs. 24%, p=0.02) and in RSV-negative patients (2.5% vs. 16.7%, p<0.05).
Conclusion:
Early treatment of bronchiolitis with oral corticosteroid in an outpatient clinic setting was associated with lower hospitalisation rates in patients with a family history of asthma or allergic rhinitis and in RSV-negative patients.
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