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Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Skin Diseases and Disorders01:23

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Skin Cancer01:30

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

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Related Experiment Videos

Primary cutaneous cryptococcosis in Hawai'i.

Christopher W M Soon1, Allan K Izumi

  • 1John A. Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, USA.

Hawaii Medical Journal
|March 27, 2007
PubMed
Summary

A man

Area of Science:

  • Dermatology
  • Mycology
  • Infectious Diseases

Background:

  • Primary cutaneous cryptococcal infections are rare fungal skin diseases.
  • Cryptococcus is an opportunistic pathogen, typically affecting immunocompromised individuals.

Observation:

  • A 72-year-old male presented with a primary cutaneous cryptococcal infection on his right forearm.
  • The lesion was initially treated with oral fluconazole at a dosage of 400 mg daily.

Findings:

  • The patient's skin lesion demonstrated a positive response to oral fluconazole treatment.
  • Complete resolution of the cutaneous cryptococcal infection was achieved after 16 weeks of therapy.
  • No scarring was observed at the site of the resolved lesion.

Implications:

Related Experiment Videos

  • This case highlights the efficacy of oral fluconazole in treating primary cutaneous cryptococcal infections.
  • Early diagnosis and treatment can lead to favorable outcomes, preventing scarring.
  • Further research may explore optimal treatment durations and dosages for similar cases.