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Related Concept Videos

Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
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IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...
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Related Experiment Video

Updated: Jul 16, 2026

Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
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Mid-ventricular ballooning heart syndrome.

Jean Marc Aubert1, Pierre Vladimir Ennezat, Olivier Tricot

  • 1Intensive Care Unit, Cardiology Hospital, Lille, France.

Echocardiography (Mount Kisco, N.Y.)
|March 27, 2007
PubMed
Summary

New research highlights a specific type of stress cardiomyopathy, termed "mid-ventricular ballooning heart syndrome," observed in women during anxious situations. This condition affects mid-left ventricular function while preserving apical and basal contractility.

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Rat Model of Right-Sided Cardiac Remodeling and Arrhythmia Using Pulmonary Artery Banding
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04:49

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Published on: June 14, 2024

Area of Science:

  • Cardiology
  • Cardiovascular Medicine
  • Clinical Cardiology

Background:

  • Stress-induced cardiomyopathies are increasingly recognized, particularly in women, often presenting as transient left ventricular apical ballooning syndrome.
  • This syndrome is frequently associated with acute emotional or physical stress.

Observation:

  • Six cases are presented where patients experienced anxious situations.
  • Echocardiograms and ventriculographies were performed to assess cardiac function.

Findings:

  • The observed condition showed mid-ventricular akinesis (lack of movement).
  • Apical and basal contractilities of the left ventricle remained preserved.
  • Coronary arteriography revealed normal coronary arteries, ruling out obstructive coronary artery disease.

Implications:

  • The findings suggest a distinct subtype of stress cardiomyopathy.
  • This
  • mid-ventricular ballooning heart syndrome
  • may require specific diagnostic and management considerations.
  • Further research is warranted to understand the pathophysiology and long-term outcomes of this syndrome.