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Updated: Jul 16, 2026

Multimodal Approach to Assess Bone Regeneration and Scaffold Performance
Published on: February 13, 2026
Evaluation of macrostructural bone biomechanics
Hélène Beaupied1, Eric Lespessailles, Claude-Laurent Benhamou
1IPROS, Inserm U658, CHR Orléans, Hôpital Porte Madeleine, 1 rue Porte Madeleine - BP 2439, 45032 Orléans Cedex 1, France. helene_beaupied@yahoo.fr
Abstract:
Bone fragility can be defined as an increased risk of fractures. Advanced age and bone diseases such as osteoporosis increase the fracture risk. Understanding the effects of osteoporosis and its treatments requires a description of the mechanical behavior of bone tissue. To this end, an entire bone can be studied, or the cortical and trabecular components can be investigated separately. We review the biomechanical tests available for measuring the ability of bone to withstand torsional, compressive, tensile, and bending forces.
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