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Updated: Jul 16, 2026

Merkel Cell Polyomavirus Infection and Detection
Published on: February 7, 2019
Complete spontaneous regression in Merkel cell carcinoma
Martin J J Vesely1, Dylan J Murray, Peter C Neligan
1Division of Plastic Surgery, University of Toronto, University Health Network, Wharton Head & Neck Centre, Toronto, Ontario, Canada.
Abstract:
Merkel cell carcinoma is a rare, aggressive, cutaneous malignancy of the elderly with a generally poor prognosis. Like all skin cancers, its incidence is rising. A few reports of spontaneous regression have been published. The case of a 67-year-old female patient who presented with a cheek Merkel cell carcinoma is described. Following biopsy it underwent complete regression with no evidence of residual tumour in the excision specimen taken seven weeks later. The current knowledge of Merkel cell carcinoma and the other cases of spontaneous regression described in the literature are reviewed.
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