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Updated: Jul 16, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
Published on: January 23, 2026
Platypnea-orthodeoxia syndrome after pneumonectomy relieved by mediastinal repositioning
Christophoros Kotoulas1, Konstantinos Patris, Konstantinos Tsintiris
1Cardiothoracic Surgery Department, Manchester Royal Infirmary, Manchester, United Kingdom. chrkotoulas@hol.gr
Abstract:
Platypnea-orthodeoxia is a rare syndrome characterized by hypoxemia in the upright position after pneumonectomy and relieved by recumbency. This syndrome is often a post-pneumonectomy complication due to intracardiac shunt, usually at the atrial level. We report a case after right pneumonectomy without interatrial shunt. The patient was successfully treated with a silicone prosthesis implant in the post-pneumonectomy space. We believe that correction of this clinical situation has not been previously described.
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