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Related Experiment Videos

Possible intranasal quetiapine misuse.

Anna K Morin1

  • 1Department of Pharmacy Practice, Massachusetts College of Pharmacy and Health Sciences, 19 Foster Street, Worcester, MA 01608, USA. anna.morin@mcphs.edu

American Journal of Health-System Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists
|March 27, 2007
PubMed
Summary
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This case report details a patient with schizoaffective disorder and substance abuse who misused quetiapine intranasally. This highlights the potential for atypical antipsychotics like quetiapine to be abused, contrary to common assumptions.

Area of Science:

  • Psychiatry
  • Pharmacology
  • Addiction Medicine

Background:

  • Schizoaffective disorder and substance abuse present complex treatment challenges.
  • Quetiapine is an atypical antipsychotic commonly prescribed for mood disorders and psychosis.
  • Substance abuse can complicate medication adherence and treatment outcomes in psychiatric patients.

Observation:

  • A patient with schizoaffective disorder and polysubstance abuse was suspected of misusing prescribed quetiapine.
  • The patient was observed hoarding quetiapine doses and later admitted to crushing and snorting the medication.
  • Physical evidence of crushed medication and white powder, suspected to be quetiapine, was found in the patient's room.

Findings:

  • The patient admitted to intranasal quetiapine misuse for perceived "calming" effects.

Related Experiment Videos

  • Symptoms consistent with cocaine withdrawal were noted, though the patient denied cocaine use.
  • Quetiapine misuse was suspected alongside concurrent substance abuse (cocaine and alcohol).

    • Implications:

    • This case suggests quetiapine may have abuse potential, challenging the perception of antipsychotics as non-abusable drugs.
    • Intranasal quetiapine misuse, previously reported in prison populations, is demonstrated in a clinical setting.
    • Healthcare providers should be vigilant for potential substance abuse of atypical antipsychotics, even in patients with diagnosed psychiatric conditions.